Refrigerant R-421A is a non-ozone-depleting HFC blend engineered as a direct replacement for R-22 in existing systems. It delivers reliable performance while allowing a smooth transition away from ozone-depleting refrigerants.
One of the key advantages of R-421A is its broad lubricant compatibility. It can be used with mineral oil, alkylbenzene (AB), or polyolester (POE) oils, helping reduce retrofit complexity and minimizing system modifications.
R-22 Replacement
Non-Ozone Depleting
Multi-Oil Compatible
ARI-700 Certified
Applications
Residential and commercial air conditioning systems
Medium-temperature refrigeration
High-temperature refrigeration applications
Commercial and industrial cooling systems
Product Quality & Assurance
When you purchase from Refrigerants Depot, you receive brand new, 100% virgin refrigerants that meet or exceed ARI-700 purity standards. Every cylinder is quality-tested to ensure dependable performance and system safety.
Shipping Information
All orders are shipped via UPS Hazmat Ground or approved freight services in full compliance with DOT regulations.
Most orders ship within 1 business day for fast and reliable delivery.